effect of honey bee venom on hyperglycemia and hyperlipidemia
- Tal Shine
- 18 ביוני
- זמן קריאה 1 דקות
Abstract
The study investigates the effect of Mongolian honey bee venom on hyperglycemia and hyperlipidemia in alloxan-induced diabetic rabbits.
Bee venom treatment resulted in a decrease in blood glucose and cholesterol levels, LDL levels, and an increase in HDL levels compared to the diabetic group.
Bee venom can be considered a therapeutic agent for diabetes, but further studies are needed to determine the best dose.
Introduction
Diabetes is characterized by high blood glucose and abnormal lipid profiles, necessitating treatments that address both.
Bee venom components like melittin and phospholipase A2 may increase insulin secretion and have lipolytic properties.
The study aims to assess the impact of Mongolian bee venom on blood glucose, cholesterol, LDL, and HDL levels in diabetic subjects.
Materials and Method
Twenty-two Chinchilla rabbits were divided into control, diabetic, and bee venom-treated groups.
Diabetes was induced in the diabetic group with Alloxan monohydrate.
The bee venom-treated group received bee stings every other day after diabetes confirmation.
Results
Blood glucose levels in the bee venom-treated group were significantly lower than in the diabetic group.
Bee venom treatment lowered plasma cholesterol levels compared to the diabetic group.
Plasma triglyceride levels were considerably lower in the bee venom-treated group.
Discussion
Bee venom treatment lowered plasma glucose, cholesterol, triglyceride, and LDL levels while increasing HDL levels in diabetic rabbits.
Bee venom may lower blood glucose by suppressing beta cell inflammation and stimulating insulin secretion.
Bee venom's phospholipase A2 may increase glucose transport and lipid uptake into adipose tissue.
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